Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.60 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.60 |
| ▸ | FASN | P49327 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908511 | 0.89 | FFAR1 (0.72) | FFAR1PLA2G2APLA2G5FASNALDH1A1 | |
| SCHEMBL10911559 | 0.87 | PLA2G2A (0.82) | FFAR1PLA2G2APLA2G5ALDH1A1MEN1 | |
| SCHEMBL10911567 | 0.87 | PLA2G2A (0.82) | FFAR1PLA2G2APLA2G5ALDH1A1MEN1 | |
| SCHEMBL10910977 | 0.87 | PLA2G2A (0.82) | FFAR1PLA2G2APLA2G5ALDH1A1MEN1 | |
| SCHEMBL10910742 | 0.86 | MEN1 (0.55) | FFAR1PLA2G2APLA2G5FASNALDH1A1 | |
| SCHEMBL10910461 | 0.83 | FFAR1 (0.60) | FFAR1PLA2G2APLA2G5FASNALDH1A1 | |
| SCHEMBL28920255 | 0.82 | FFAR1 (0.62) | FFAR1PLA2G2APLA2G5FASNALDH1A1 | |
| SCHEMBL20556365 | 0.79 | FASN (0.69) | FFAR1PLA2G2APLA2G5FASNALDH1A1 | |
| SCHEMBL9752830 | 0.78 | PLA2G2A (0.86) | FFAR1PLA2G2APLA2G5FASNALDH1A1 | |
| SCHEMBL9752583 | 0.77 | PLA2G2A (0.96) | FFAR1PLA2G2APLA2G5FASNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069536-B1 | PHLOROPHENONE DERIVATIVES, PROCESSES FOR PREPARING SUCH COMPOUNDS, USES AND PHARMACEUTICAL COMPOSITIONS OF PHLOROPHENONE COMPOUNDS | NORISTAN LIMITED (ZA) | 1986-12-17 | — | — | EP | disclosed |
| US-4578520-A | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1986-03-25 | — | — | US | disclosed |
| US-4503256-A | BACTERICIDES, FUNGICIDES | NORISTAN LIMITED (ZA) | 1985-03-05 | — | — | US | disclosed |
| EP-0069536-A1 | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1983-01-12 | — | — | EP | disclosed |