Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176825 | 0.88 | EPHX1 (0.52) | SIRT2SIRT1EPHX1CASP2 | |
| SCHEMBL22365675 | 0.88 | EPHX1 (0.52) | SIRT2SIRT1EPHX1CASP2 | |
| SCHEMBL11318989 | 0.88 | EPHX1 (0.52) | SIRT2SIRT1EPHX1CASP2 | |
| SCHEMBL11309804 | 0.88 | EPHX1 (0.52) | SIRT2SIRT1EPHX1CASP2 | |
| SCHEMBL18248636 | 0.88 | EPHX1 (0.52) | SIRT2SIRT1EPHX1CASP2 | |
| SCHEMBL14957807 | 0.88 | EPHX1 (0.52) | SIRT2SIRT1EPHX1CASP2 | |
| SCHEMBL9879639 | 0.88 | EPHX1 (0.50) | DNM1EPHX1CASP2 | |
| SCHEMBL18256335 | 0.82 | FAAH (0.48) | SIRT2SIRT1SIRT3EPHX1CASP2 | |
| SCHEMBL10909152 | 0.80 | SELP (0.47) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL24682149 | 0.77 | SLC6A5 (0.73) | SLC6A5DNM1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618416-A | COLLECTORS FOR METAL SULFIDE MINERALS; FROTH FLOATATION | SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) | 1986-10-21 | — | — | US | disclosed |