Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654446 | 0.83 | RXRA (0.47) | SLC6A2SLC6A4RXRARXRBRXRG | |
| SCHEMBL4654255 | 0.83 | DRD1 (0.48) | SLC6A2SLC6A4SLC22A12DRD1KMT2A | |
| SCHEMBL10911708 | 0.81 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC22A12RXRARXRB | |
| SCHEMBL10910618 | 0.81 | DRD1 (0.39) | SLC22A12DRD1KMT2AULK1HTT | |
| SCHEMBL3719913 | 0.75 | ALDH1A1 (0.37) | SLC6A2SLC6A4RXRARXRBRXRG | |
| SCHEMBL1068429 | 0.75 | — | — | |
| SCHEMBL1069181 | 0.75 | — | — | |
| SCHEMBL1063855 | 0.74 | KCNK3 (0.30) | KCNK3KCNK9 | |
| SCHEMBL1068899 | 0.74 | SLC22A12 (0.32) | SLC22A12DRD1ULK1DDB1CRBN | |
| SCHEMBL23813151 | 0.73 | ALDH1A1 (0.48) | DRD1KMT2AHTTSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124002-B1 | PROCESS FOR THE PREPARATION OF AROMATIC COMPOUNDS CONTAINING PERFLUORINATED SIDE CHAINS LINKED BY A HETEROATOM | BAYER AG (DE) | 1986-11-12 | — | — | EP | disclosed |
| US-4600787-A | Process for the preparation of aromatic compounds which contain perfluorinated side-chains bonded via a heteroatom | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | disclosed |
| EP-0124002-A1 | Process for the preparation of aromatic compounds containing perfluorinated side chains linked by a heteroatom | BAYER AG (DE) | 1984-11-07 | — | — | EP | disclosed |