SCHEMBL10908798

SCHEMBL10908798

C=CC[Si](OC(=O)c1ccccc1)(OC(=O)c1ccccc1)OC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.47
LMNA P02545 3/20 0.45
F2 P00734 1/20 0.45
TDP1 Q9NUW8 3/20 0.43
TSHR P16473 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
CYP3A4 P08684 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 1/20 0.39
TP53 P04637 1/20 0.39
PLA2G7 Q13093 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10910774 0.84 TSHR (0.46) AKT1LMNAF2TDP1TSHR
SCHEMBL10911268 0.83 TSHR (0.44) AKT1LMNAF2TDP1TSHR
SCHEMBL253482 0.76 TDP1 (0.49) AKT1LMNAF2TDP1TSHR
SCHEMBL10908800 0.76 CYP3A4 (0.46) AKT1LMNAF2TDP1TSHR
SCHEMBL10908916 0.76 LMNA (0.50) AKT1LMNAF2TDP1TSHR
SCHEMBL10908921 0.73 LMNA (0.47) AKT1LMNAF2TDP1TSHR
SCHEMBL10912113 0.73 TSHR (0.48) AKT1LMNAF2TDP1TSHR
SCHEMBL10908802 0.73 TSHR (0.48) AKT1LMNAF2TDP1TSHR
SCHEMBL10912072 0.72 LMNA (0.46) AKT1LMNAF2TDP1TSHR
SCHEMBL10733991 0.72 LMNA (0.61) LMNAF2TDP1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4584394-A REACTING ALKENYLAKOXYSILANE WITH BENZOIC ACID ANHYDRIDE DYNAMIT NOBEL AG (DE) 1986-04-22 US claimed
US-4584394-A REACTING ALKENYLAKOXYSILANE WITH BENZOIC ACID ANHYDRIDE DYNAMIT NOBEL AG (DE) 1986-04-22 US disclosed
EP-0148398-A2 Alkenylbenzoyloxysilanes and their use in adhesives HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1985-07-17 EP disclosed