Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912113 | 0.85 | TSHR (0.48) | TSHRLMNAF2AKT1TDP1 | |
| SCHEMBL10908916 | 0.81 | LMNA (0.50) | TSHRLMNAF2AKT1TDP1 | |
| SCHEMBL10910774 | 0.79 | TSHR (0.46) | TSHRLMNAF2AKT1TDP1 | |
| SCHEMBL10909678 | 0.79 | TSHR (0.50) | TSHRLMNAF2AKT1TDP1 | |
| SCHEMBL10912862 | 0.79 | TSHR (0.50) | TSHRLMNAF2AKT1TDP1 | |
| SCHEMBL203317 | 0.78 | TSHR (0.58) | TSHRLMNAF2TDP1ALDH1A1 | |
| SCHEMBL7070049 | 0.78 | TSHR (0.58) | TSHRLMNAF2TDP1ALDH1A1 | |
| SCHEMBL1759366 | 0.78 | TSHR (0.58) | TSHRLMNAF2TDP1ALDH1A1 | |
| SCHEMBL10911268 | 0.77 | TSHR (0.44) | TSHRLMNAF2AKT1TDP1 | |
| SCHEMBL10912072 | 0.77 | LMNA (0.46) | TSHRLMNAF2AKT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584394-A | REACTING ALKENYLAKOXYSILANE WITH BENZOIC ACID ANHYDRIDE | DYNAMIT NOBEL AG (DE) | 1986-04-22 | — | — | US | disclosed |
| EP-0148398-A2 | Alkenylbenzoyloxysilanes and their use in adhesives | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1985-07-17 | — | — | EP | disclosed |