SCHEMBL10908856

SCHEMBL10908856

Cc1cc(-c2ccc(C(=O)O)c(-c3ccc(O)c(C)c3)c2C(=O)O)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 0.49
ACMSD Q8TDX5 5/20 0.41
DHFR P00374 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
TTR P02766 1/20 0.41
ALB P02768 1/20 0.41
HMGB1 P09429 1/20 0.41
HPGD P15428 1/20 0.41
CXCL12 P48061 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
CSNK2A1 P68400 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10908147 0.88 MCL1 (0.49) MCL1ACMSDDHFRHSD17B10ALDH1A1
SCHEMBL10908346 0.86 MCL1 (0.59) MCL1ACMSDDHFRCSNK2A1IL1B
SCHEMBL10906083 0.82 CA1 (0.44) MCL1ACMSDDHFRHSD17B10ALDH1A1
SCHEMBL10908355 0.82 RARB (0.49) MCL1ACMSDDHFRHSD17B10ALDH1A1
SCHEMBL31001742 0.76 MCL1 (0.51) MCL1ACMSDDHFRHSD17B10ALDH1A1
SCHEMBL10610933 0.74 MCL1 (0.49) MCL1CSNK2A1IL1BHCAR2RXRB
SCHEMBL8948814 0.73 CYP1A2 (0.49) ACMSDHSD17B10ALDH1A1KDM4EMEN1
SCHEMBL17384089 0.73 HNF4A (0.61) MCL1ACMSDALDH1A1CA1CA2
SCHEMBL10783650 0.73 FOLH1 (0.54) KDM4ERXRBRXRA
SCHEMBL11043030 0.72 KMT2A (0.44) MCL1HSD17B10ALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4570170-A IMAGE KEEPING QUALITY STABILIZER; BIS(HYDROXYPHENYL) PHTHALATES MITSUBISHI PAPER MILLS, LTD. (JP) 1986-02-11 US disclosed