SCHEMBL8948814

SCHEMBL8948814

O=C(O)c1ccc2cc(-c3ccc(C(=O)O)c(-c4ccc5cc(C(=O)O)ccc5c4)c3C(=O)O)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
CYP2C19 P33261 1/20 0.49
SOS1 Q07889 1/20 0.49
HIF1A Q16665 1/20 0.49
RARB P10826 7/20 0.43
RARG P13631 7/20 0.43
RARA P10276 5/20 0.42
KDM4E B2RXH2 3/20 0.41
PTPN11 Q06124 3/20 0.40
PTPN1 P18031 1/20 0.40
FOLH1 Q04609 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ACMSD Q8TDX5 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948583 0.90 CYP1A2 (0.46) CYP1A2CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL10783650 0.82 FOLH1 (0.54) KDM4EPTPN11FOLH1
SCHEMBL9443383 0.81 RARB (0.49) CYP1A2CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL8948605 0.81 FOLH1 (0.47) CYP2C9TSHRPTPN11FOLH1SMN1; SMN2
SCHEMBL8948602 0.80 PTPN1 (0.57) CYP1A2CYP2D6CYP2C9TSHRCYP2C19
Terephthalic Acid SCHEMBL11120261 0.75 CDC25B (0.46) CYP2C9TSHRKDM4EPTPN1FOLH1
SCHEMBL13900230 0.75 RARB (0.64) TSHRRARBRARGRARAKDM4E
SCHEMBL5842542 0.74 ACMSD (0.55) CYP1A2CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL8948670 0.74 FOLH1 (0.38) CYP1A2CYP2D6CYP2C9TSHRCYP2C19
Terephthalic Acid SCHEMBL5494019 0.74 CYP2C8 (0.47) CYP2C9TSHRKDM4EFOLH1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525699-A Copolymers having a controlled sequence structure HOECHST CELANESE CORP. (US) 1996-06-11 US disclosed
EP-0569930-A2 Copolymers having a controlled sequence structure HOECHST CELANESE CORPORATION (US) 1993-11-18 EP disclosed
US-5256760-A Forming controlled sequence condensation copolymers HOECHST CELANESE CORP. (US) 1993-10-26 US disclosed