Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677076 | 0.87 | RAB9A (0.51) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL10906771 | 0.84 | MAPT (0.49) | KMT2AMEN1SMN1; SMN2POLBTSHR | |
| SCHEMBL11671141 | 0.80 | RAB9A (0.46) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL11712687 | 0.80 | MEN1 (0.46) | KMT2ARAB9AMEN1SMN1; SMN2POLB | |
| SCHEMBL11049540 | 0.80 | RAB9A (0.48) | NPC1KMT2ARAB9AMEN1POLB | |
| SCHEMBL10908923 | 0.79 | HPGD (0.46) | NPC1KMT2ARAB9AMEN1MTNR1A | |
| SCHEMBL11797782 | 0.78 | MEN1 (0.55) | NPC1KMT2ARAB9AMEN1POLB | |
| SCHEMBL8394565 | 0.78 | POLB (0.50) | KMT2ARAB9AMEN1POLBTSHR | |
| SCHEMBL3480132 | 0.78 | MEN1 (0.44) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL10526825 | 0.78 | NPC1 (0.50) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564673-A | 3-Cyano-5-nitrothiophene anilino monoazo dye for synthetic fibers | RESEARCH ASSOCIATION OF SYNTHETIC DYESTUFFS (JP) | 1986-01-14 | — | — | US | disclosed |