Amylene Hydrate

Amylene Hydrate

SCHEMBL10909206

CCC(C)(C)O.CN.c1ccccc1

nearest known ligand 0.39

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 2/20 0.31
SLC6A2 P23975 1/20 0.31
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amylene Hydrate SCHEMBL2677237 0.93 ALDH1A1 (0.44) ALDH1A1TSHRTDP1MEN1GAA
Amylene Hydrate SCHEMBL28975070 0.86
Amylene Hydrate SCHEMBL29246481 0.82
Amylene Hydrate SCHEMBL9631192 0.82
Amylene Hydrate SCHEMBL2013421 0.82 ALDH1A1 (0.54) ALDH1A1TSHRTDP1HMGCRCHRM1
Amylene Hydrate SCHEMBL10721 0.82
Amylene Hydrate SCHEMBL28767318 0.79
Amylene Hydrate SCHEMBL9619268 0.78
Amylene Hydrate SCHEMBL7624044 0.78
Amylene Hydrate SCHEMBL9619592 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4591551-A ENZYMATIC TRANSMETHYLATION UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1986-05-27 US disclosed