Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amylene Hydrate SCHEMBL10909206 | 0.93 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1MEN1GAA | |
| Amylene Hydrate SCHEMBL28975070 | 0.92 | — | — | |
| Amylene Hydrate SCHEMBL29246481 | 0.88 | — | — | |
| Amylene Hydrate SCHEMBL2013421 | 0.88 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1HMGCRCHRM1 | |
| Amylene Hydrate SCHEMBL9631192 | 0.88 | — | — | |
| Amylene Hydrate SCHEMBL10721 | 0.88 | — | — | |
| Amylene Hydrate SCHEMBL9644533 | 0.84 | — | — | |
| Amylene Hydrate SCHEMBL9619268 | 0.84 | — | — | |
| Amylene Hydrate SCHEMBL22233971 | 0.84 | — | — | |
| Amylene Hydrate SCHEMBL5499858 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679518-B2 | Antimicrobial compounds having protective or therapeutic leaving groups | MEDTRONIC, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120157373-A1 | ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS | MEDTRONIC, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-8173622-B2 | Antimicrobial compounds having protective or therapeutic leaving groups | MEDTRONIC, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| WO-2010019530-A1 | ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS | MEDTRONIC, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20090047321-A1 | ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS | MEDTRONIC, INC. (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157373-A1 | ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS | LTN1, VIP, CTSA | ALDH1A1 593/4885TSHR 4590/4885TDP1 4131/4885 |
| US-20090047321-A1 | ANTIMICROBIAL COMPOUNDS HAVING PROTECTIVE OR THERAPEUTIC LEAVING GROUPS | LTN1, VIP, CTSA | ALDH1A1 593/4885TSHR 4590/4885TDP1 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.