Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.38 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | USP8 | P40818 | 3/20 | 0.34 |
| ▸ | USP7 | Q93009 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131672 | 0.80 | USP8 (0.34) | ALDH1A1USP8USP7MCL1UPP1 | |
| SCHEMBL4342916 | 0.79 | USP8 (0.53) | KDM4EALDH1A1USP8USP7MEN1 | |
| SCHEMBL8099021 | 0.79 | USP8 (0.33) | USP8USP7UPP1 | |
| SCHEMBL31409756 | 0.75 | USP8 (0.33) | ALDH1A1USP8USP7HSP90AA1UPP1 | |
| SCHEMBL615483 | 0.75 | USP8 (0.53) | DNMT1KDM4EALDH1A1USP8USP7 | |
| SCHEMBL1453039 | 0.72 | TDP2 (0.33) | ALDH1A1USP8USP7HSP90AA1CYP1A2 | |
| SCHEMBL11426926 | 0.69 | PARP1 (0.42) | KDM4EALDH1A1MEN1KMT2AGAA | |
| Dichlon SCHEMBL4532122 | 0.68 | IDO1 (0.64) | IDO1DNMT1DNMT3LDNMT3AKDM4E | |
| SCHEMBL11560096 | 0.67 | ADORA2A (0.46) | IDO1DNMT1DNMT3LDNMT3AKDM4E | |
| SCHEMBL152358 | 0.66 | TSHR (0.39) | KDM4EALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614807-A | ANTIFERTILITY AGENTS | ELI LILLY AND COMPANY (US) | 1986-09-30 | — | — | US | disclosed |