SCHEMBL615483

SCHEMBL615483

N#Cc1ccc2c(c1C#N)C(=O)c1ccccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP8 P40818 2/20 0.53
USP7 Q93009 2/20 0.53
ALDH1A1 P00352 5/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPT P10636 6/20 0.41
MAOA P21397 5/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPK1 P28482 3/20 0.41
KDM4E B2RXH2 3/20 0.41
LMNA P02545 2/20 0.41
PPARG P37231 2/20 0.41
HTT P42858 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
RECQL P46063 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
S100A4 P26447 2/20 0.41
PTPRC P08575 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4342916 0.93 USP8 (0.53) USP8USP7ALDH1A1CYP1A2CYP2C9
SCHEMBL8726525 0.80 USP8 (0.38) USP8USP7ALDH1A1MAPTMAOA
SCHEMBL9265082 0.79 USP8 (0.58) USP8USP7ALDH1A1MAPTMAOA
SCHEMBL163577 0.77 USP8 (0.56) USP8USP7ALDH1A1CYP1A2CYP2C9
SCHEMBL295307 0.77 ALDH1A1 (0.49) USP8USP7ALDH1A1CYP1A2CYP2C9
SCHEMBL131672 0.76 USP8 (0.34) USP8USP7ALDH1A1CYP1A2CYP2C9
SCHEMBL8099021 0.75 USP8 (0.33) USP8USP7
SCHEMBL10909262 0.75 IDO1 (0.38) USP8USP7ALDH1A1CYP1A2CYP2C9
Methane SCHEMBL28696439 0.75 ALDH1A1 (0.47) USP8USP7ALDH1A1CYP1A2CYP2C9
Methane SCHEMBL4141657 0.75 ALDH1A1 (0.47) USP8USP7ALDH1A1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100099815-A1 COUPLED CHARGE TRANSFER NANOTUBE DOPANTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2010-04-22 US claimed
EP-2158623-A1 COUPLED CHARGE TRANSFER NANOTUBE DOPANTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2010-03-03 EP claimed
WO-2008103703-A1 COUPLED CHARGE TRANSFER NANOTUBE DOPANTS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-08-28 WO claimed
US-20230288827-A1 PHOTOSENSITIVE BODY INCLUDING PROTECTIVE LAYER HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-09-14 US disclosed
US-11554572-B2 Desiccant, organic thin film including same, organic layered film in which organic thin film is layered, and electronic device provided therewith Konica Minolta, Inc. (JP) 2023-01-17 US disclosed
EP-4052096-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR CAPABLE OF SUPPRESSING MICRO-JITTER IMAGE DEFECT Hewlett-Packard Development Company, L.P. (US) 2022-09-07 EP disclosed
WO-2022181281-A1 SEALANT COMPOSITION, SEMICONDUCTOR SEALING MATERIAL, AND SEMICONDUCTOR コニカミノルタ株式会社 2022-09-01 WO disclosed
US-20220214628-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR CAPABLE OF SUPPRESSING MICRO-JITTER IMAGE DEFECT HEWLETT- PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-07-07 US disclosed
US-11276837-B2 Manufacturing method for electronic device Konica Minolta, Inc. (JP) 2022-03-15 US disclosed
WO-2022025881-A1 PHOTOSENSITIVE BODY INCLUDING PROTECTIVE LAYER HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-02-03 WO disclosed
EP-3453746-B1 GEL-FORM COMPOSITION AND WATER ABSORPTION INHIBITOR SHINETSU CHEMICAL CO (JP) 2020-12-09 EP disclosed
EP-0780442-B1 Derivatives of diiminoquinilidines useful as electron transport agents in electrophotographic elements HEWLETT PACKARD CO (US) 2001-07-11 EP disclosed
EP-0780365-B1 Derivatives of diiminoquinones useful as electron transport agents in electrophotographic elements HEWLETT PACKARD CO (US) 2000-04-05 EP disclosed
EP-0780442-A1 Derivatives of diiminoquinilidines useful as electron transport agents in electrophotographic elements Hewlett-Packard Company (US) 1997-06-25 EP disclosed
EP-0780365-A1 Derivatives of diiminoquinones useful as electron transport agents in electrophotographic elements Hewlett-Packard Company (US) 1997-06-25 EP disclosed
US-5631114-A COLOR ELECTROGRAPHIC PRINTING HEWLETT-PACKARD COMPANY (US) 1997-05-20 US disclosed
EP-0554110-B1 Processes for the preparation of photogenerating compositions XEROX CORP (US) 1997-05-07 EP disclosed
US-5558965-A Diiminoquinilidines as electron transport agents in electrophotographic elements HEWLETT-PACKARD COMPANY (US) 1996-09-24 US disclosed
EP-0554110-A1 Processes for the preparation of photogenerating compositions XEROX CORPORATION (US) 1993-08-04 EP disclosed
US-5225307-A Sublimation of pelletized photogenerating pigment XEROX CORPORATION (US) 1993-07-06 US disclosed