Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | RECQL | P46063 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343207 | 0.93 | KMT2A (0.58) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL10909467 | 0.91 | KMT2A (0.50) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL10908602 | 0.89 | KMT2A (0.54) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL10907534 | 0.88 | CD40 (0.50) | KMT2ATIMP3MEN1CCR8PRMT1 | |
| SCHEMBL10907796 | 0.85 | KMT2A (0.49) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL10907632 | 0.85 | KMT2A (0.52) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL11427817 | 0.84 | HSD17B10 (0.50) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL11349457 | 0.83 | KMT2A (0.58) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL10908320 | 0.83 | KMT2A (0.45) | KMT2ARECQLHSD17B10TDP1TIMP3 | |
| SCHEMBL11335520 | 0.82 | TIMP3 (0.63) | KMT2ARECQLHSD17B10TDP1TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |