Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341082 | 0.93 | KMT2A (0.53) | KMT2AMEN1TIMP3USP2RECQL | |
| SCHEMBL10908295 | 0.91 | KMT2A (0.45) | KMT2AMEN1TIMP3USP2RECQL | |
| SCHEMBL10907950 | 0.89 | MEN1 (0.47) | KMT2AMEN1TIMP3USP2RECQL | |
| SCHEMBL10907905 | 0.88 | MPL (0.48) | KMT2AMEN1TIMP3RECQLMPL | |
| SCHEMBL9343077 | 0.86 | MPL (0.50) | MPLNSD2CCR8 | |
| SCHEMBL10907792 | 0.85 | KMT2A (0.47) | KMT2AMEN1TIMP3USP2RECQL | |
| SCHEMBL11424878 | 0.84 | KDM4E (0.49) | KMT2AMEN1HSD17B10ALDH1A1MPL | |
| SCHEMBL11339069 | 0.83 | KMT2A (0.53) | KMT2AMEN1TIMP3USP2RECQL | |
| SCHEMBL10909358 | 0.83 | KMT2A (0.50) | KMT2AMEN1TIMP3USP2RECQL | |
| SCHEMBL10905547 | 0.82 | NPC1 (0.47) | KMT2AMEN1TIMP3USP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |