Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24804434 | 0.85 | HTT (0.50) | HTTHPGDPTGS1PTGS2ALDH1A1 | |
| SCHEMBL8024047 | 0.84 | BACE1 (0.62) | PTPN1MAOB | |
| SCHEMBL10871362 | 0.84 | CA12 (0.49) | HTTHPGDPTGS1PTGS2ALDH1A1 | |
| SCHEMBL10871358 | 0.84 | CA12 (0.49) | HTTHPGDPTGS1PTGS2ALDH1A1 | |
| Prenylhydroquinone SCHEMBL7036748 | 0.82 | HTT (0.64) | HTTHPGDPTGS1PTGS2ALDH1A1 | |
| SCHEMBL10907779 | 0.81 | HTT (0.62) | HTTHPGDPTGS1PTGS2ALDH1A1 | |
| SCHEMBL13982775 | 0.81 | HTT (0.47) | HTTHPGDPTGS1PTGS2ALDH1A1 | |
| SCHEMBL13284802 | 0.80 | AMY1A (0.55) | HTTHPGDALDH1A1AMY1AMEN1 | |
| SCHEMBL21363082 | 0.79 | HTT (0.41) | HTTHPGDPTGS1PTGS2ALDH1A1 | |
| SCHEMBL10908436 | 0.79 | HTT (0.60) | HTTHPGDPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023197248-A1 | BIOLOGICAL AGENT AND METHOD FOR PROMOTING ADIPOGENIC DIFFERENTIATION OF MESENCHYMAL STEM CELLS AND LIPOGENESIS OF ADIPOCYTE PRECURSOR CELLS | 厦门千夫海洋生物科技有限公司 | 2023-10-19 | — | — | WO | disclosed |
| WO-2023197249-A1 | DRUG FOR IMPROVING SPERM MOTILITY AND INHIBITING SPERM DFI AND METHOD FOR IMPROVING SPERM MOTILITY AND INHIBITING SPERM DFI | 厦门千夫海洋生物科技有限公司 | 2023-10-19 | — | — | WO | disclosed |
| WO-2019178119-A1 | AMINOCOUMARIN COMPOUNDS AND METHODS OF THEIR USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-09-19 | — | — | WO | disclosed |
| US-20160289217-A1 | COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS | UNIVERSITY OF KANSAS (US) | 2016-10-06 | — | — | US | disclosed |
| US-20160272584-A1 | BIPHENYLAMIDE DERIVATIVE HSP90 INHIBITORS | UNIVERSITY OF KANSAS (US) | 2016-09-22 | — | — | US | disclosed |
| US-4594460-A | Process for selective C-alkylation of phenols | RHONE-POULENC SANTE (FR) | 1986-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289217-A1 | COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS | HSP90B1, HSP90AA1, HSP90AB1 | HTT 530/4885HPGD 711/4885PTGS1 1340/4885 |
| US-20160272584-A1 | BIPHENYLAMIDE DERIVATIVE HSP90 INHIBITORS | HSP90AB1, HSP90AA1, HSP90AB2P | HTT 285/4885HPGD 812/4885PTGS1 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.