Prenylhydroquinone

Prenylhydroquinone

SCHEMBL7036748

CC(C)=CCc1cc(O)ccc1O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.64
PTGS1 P23219 2/20 0.63
PTGS2 P35354 2/20 0.63
HPGD P15428 2/20 0.58
ALDH1A1 P00352 1/20 0.58
PTPN1 P18031 5/20 0.57
AKR1B10 O60218 1/20 0.55
AKR1B1 P15121 1/20 0.55
AKR1C3 P42330 1/20 0.55
MEN1 O00255 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
CYP19A1 P11511 2/20 0.51
MGAM O43451 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prenylhydroquinone SCHEMBL5823293 0.91 HTT (0.59) HTTPTGS1PTGS2HPGDALDH1A1
Geroquinol SCHEMBL29929565 0.85 ALOX5 (0.57) PTPN1MAOB
Geroquinol SCHEMBL557012 0.85 ALOX5 (0.57) PTPN1MAOB
Geroquinol SCHEMBL557013 0.85 ALOX5 (0.57) PTPN1MAOB
SCHEMBL8698637 0.84 TYR (0.54) HTTPTGS1PTGS2HPGDALDH1A1
SCHEMBL8017471 0.84 ALOX5 (0.59) PTPN1MAOB
SCHEMBL2943955 0.84 ALOX5 (0.59) PTPN1MAOB
Geranylgeranylhydroquinone SCHEMBL8025990 0.84 ALOX5 (0.59) PTPN1MAOB
SCHEMBL31536036 0.84 ALOX5 (0.59) PTPN1MAOB
SCHEMBL19600971 0.83 PTGS1 (0.46) HTTPTGS1PTGS2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3212176-B1 PANICEIN COMPOUNDS, COMPOSITIONS AND THEIR USE IN THE TREATMENT OF CANCER CENTRE NAT RECH SCIENT (FR) 2020-11-04 EP disclosed
US-20170326076-A1 PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-11-16 US disclosed
WO-2017004730-A1 PESTICIDE COMPOSITION COMPRISING TWO ACETYLATED COMPOUNDS OF PRENYLATED HYDROQUINONE AND ORCINOL COMPOUNDS AND USE THEREOF AS FUNGICIDES IN CONTROLLING BOTRYTIS CINEREA UNIVERSIDAD TÉCNICA FEDERICO SANTA MARÍA (CL) 2017-01-12 WO disclosed
WO-2016066594-A1 PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-05-06 WO disclosed
US-7410998-B2 Inhibitors of NADH:ubiquinone oxidoreductase THE SCRIPPS RESEARCH INSTITUTE (US) 2008-08-12 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
WO-2002100478-A9 ACCELERATORS FOR INCREASING THE RATE OF FORMATION OF FREE RADICALS AND REACTIVE OXYGEN SPECIES CAVALIER DISCOVERY (US) 2003-03-27 WO disclosed
WO-2002100478-A2 ACCELERATORS FOR INCREASING THE RATE OF FORMATION OF FREE RADICALS AND REACTIVE OXYGEN SPECIES CAVALIER DISCOVERY (US) 2002-12-19 WO disclosed
US-4594460-A Process for selective C-alkylation of phenols RHONE-POULENC SANTE (FR) 1986-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170326076-A1 PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF ABCC1, ABCB1, SLC47A1 HTT 3273/4885PTGS1 871/4885PTGS2 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.