Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR5A | P47898 | 3/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829116 | 0.88 | SRC (0.54) | SRCHTR2CHTR1AHTR1DHTR7 | |
| SCHEMBL10913727 | 0.84 | SRC (0.56) | SRCPARP1REN | |
| SCHEMBL2333682 | 0.81 | SRC (0.60) | SRCHTR2CHTR5APARP1REN | |
| SCHEMBL18355372 | 0.77 | SRC (0.56) | SRCPARP1REN | |
| SCHEMBL10911476 | 0.77 | SRC (0.56) | SRCHTR2CADRA2AADRA2BADRA2C | |
| SCHEMBL7029485 | 0.76 | SRC (0.58) | SRCPARP1REN | |
| SCHEMBL13439627 | 0.76 | SRC (0.51) | SRCPARP1 | |
| SCHEMBL28092163 | 0.75 | SRC (0.61) | SRCPARP1HTR2A | |
| SCHEMBL9910075 | 0.75 | SRC (0.49) | SRCHTR2CHTR2B | |
| SCHEMBL16174360 | 0.74 | SRC (0.42) | SRCPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173208-A1 | Tetrahydroquinolin-1-yl-carbonyl-imidazole derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-05 | — | — | EP | disclosed |