Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912135 | 0.84 | SRC (0.56) | SRCPARP1SLC13A5REN | |
| SCHEMBL2333682 | 0.81 | SRC (0.60) | SRCPARP1RENPNMT | |
| SCHEMBL10911476 | 0.77 | SRC (0.56) | SRCPARP1REN | |
| SCHEMBL10909385 | 0.77 | SRC (0.56) | SRCPARP1REN | |
| SCHEMBL7029485 | 0.76 | SRC (0.58) | SRCPARP1SLC13A5RENF2 | |
| SCHEMBL10912802 | 0.76 | SRC (0.46) | SRCPARP1SLC13A5F2 | |
| SCHEMBL28092163 | 0.75 | SRC (0.61) | SRCPARP1SLC13A5 | |
| SCHEMBL9829116 | 0.75 | SRC (0.54) | SRCPARP1SLC13A5RENF2 | |
| SCHEMBL10913727 | 0.74 | SRC (0.56) | SRCPARP1SLC13A5RENKCNH2 | |
| SCHEMBL9829123 | 0.74 | SRC (0.56) | SRCPARP1RENF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001990-A1 | PIPERIDINE-DIONE DERIVATIVES | GENENTECH, INC. (US) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001990-A1 | PIPERIDINE-DIONE DERIVATIVES | DRD4, ADORA1, ADORA3 | SRC 4285/4885PARP1 207/4885SLC13A5 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.