Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346020 | 0.94 | PRMT1 (0.50) | NT5EPRMT1LMNAUSP2MAPK1 | |
| SCHEMBL10907874 | 0.93 | NT5E (0.46) | NT5EPRMT1LMNAUSP2MAPK1 | |
| SCHEMBL11341950 | 0.86 | PRMT1 (0.55) | NT5EPRMT1LMNAUSP2MAPK1 | |
| SCHEMBL10907751 | 0.85 | NT5E (0.40) | NT5EPRMT1LMNAUSP2MAPK1 | |
| SCHEMBL10909113 | 0.85 | NT5E (0.53) | NT5EPRMT1LMNAUSP2MAPK1 | |
| SCHEMBL10908189 | 0.83 | PRMT1 (0.43) | NT5EPRMT1LMNAUSP2HSD17B10 | |
| SCHEMBL10909110 | 0.83 | CTDSP1 (0.50) | NT5EPRMT1CASP6CTDSP1ALDH1A1 | |
| SCHEMBL10908524 | 0.83 | PRMT1 (0.42) | NT5EPRMT1LMNAUSP2HSD17B10 | |
| SCHEMBL10909518 | 0.82 | NT5E (0.61) | NT5EPRMT1LMNAUSP2MAPK1 | |
| SCHEMBL10908508 | 0.81 | PRMT1 (0.57) | NT5EPRMT1LMNAUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |