Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338837 | 0.93 | TIMP3 (0.53) | CTDSP1CASP6CA1CA2ENPP2 | |
| SCHEMBL10907702 | 0.92 | CASP6 (0.55) | CTDSP1CASP6CA1CA2ENPP2 | |
| SCHEMBL10909529 | 0.87 | KMT2A (0.46) | CTDSP1CASP6TIMP3NT5EPRMT1 | |
| SCHEMBL11440941 | 0.86 | CASP6 (0.60) | CTDSP1CASP6CA1CA2ENPP2 | |
| SCHEMBL11350531 | 0.84 | PRMT1 (0.57) | CTDSP1CASP6CA1CA2ENPP2 | |
| SCHEMBL11431481 | 0.83 | RAB9A (0.56) | CTDSP1CASP6CA1CA2CA9 | |
| SCHEMBL10905197 | 0.83 | CASP6 (0.59) | CTDSP1CASP6CA1CA2ENPP2 | |
| SCHEMBL10909096 | 0.83 | TIMP3 (0.50) | CTDSP1CASP6CA1CA2ENPP2 | |
| SCHEMBL10909449 | 0.83 | NT5E (0.42) | CTDSP1CASP6CA2NT5EPRMT1 | |
| SCHEMBL10908164 | 0.81 | TIMP3 (0.51) | CTDSP1CASP6CA1CA2TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |