Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344584 | 0.94 | PRMT1 (0.47) | NT5ELMNAUSP2HSD17B10MAPK1 | |
| SCHEMBL10907727 | 0.93 | ENPP2 (0.45) | NT5ELMNAUSP2HSD17B10MAPK1 | |
| SCHEMBL11340814 | 0.86 | PRMT1 (0.52) | NT5EUSP2HSD17B10PRMT1ENPP2 | |
| SCHEMBL10908189 | 0.86 | PRMT1 (0.43) | NT5ELMNAUSP2HSD17B10PRMT1 | |
| SCHEMBL10909449 | 0.85 | NT5E (0.42) | NT5ELMNAUSP2HSD17B10MAPK1 | |
| SCHEMBL10908524 | 0.85 | PRMT1 (0.42) | NT5ELMNAUSP2HSD17B10PRMT1 | |
| SCHEMBL10909096 | 0.83 | TIMP3 (0.50) | NT5EPRMT1ENPP2TIMP3MEN1 | |
| SCHEMBL10909167 | 0.83 | SNCA (0.43) | NT5ELMNAUSP2HSD17B10MAPK1 | |
| SCHEMBL10909113 | 0.83 | NT5E (0.53) | NT5ELMNAUSP2HSD17B10MAPK1 | |
| SCHEMBL10908090 | 0.82 | PRMT1 (0.46) | NT5ELMNAUSP2HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |