Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10366169 | 0.93 | MEN1 (0.40) | ALDH1A1RECQLMEN1LMNAMAPT | |
| SCHEMBL10907131 | 0.81 | GAA (0.42) | ALDH1A1MEN1LMNAMAPTKMT2A | |
| Bromide SCHEMBL10365168 | 0.80 | GAA (0.41) | ALDH1A1MEN1LMNAMAPTKMT2A | |
| SCHEMBL10365911 | 0.75 | ALDH1A1 (0.49) | ALDH1A1RECQLMEN1LMNAMAPT | |
| Bromide SCHEMBL10366163 | 0.70 | ALDH1A1 (0.50) | ALDH1A1RECQLMEN1LMNAMAPT | |
| SCHEMBL10909585 | 0.70 | MEN1 (0.47) | ALDH1A1RECQLMEN1LMNAMAPT | |
| SCHEMBL10365808 | 0.70 | MAPT (0.47) | ALDH1A1RECQLMEN1LMNAMAPT | |
| SCHEMBL10366284 | 0.69 | ALDH1A1 (0.46) | ALDH1A1RECQLMEN1LMNAMAPT | |
| SCHEMBL8305160 | 0.69 | MAPT (0.56) | ALDH1A1RECQLMEN1LMNAMAPT | |
| SCHEMBL10366286 | 0.69 | MEN1 (0.46) | ALDH1A1RECQLMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588727-A | ANALGESICS, TRANQUILLIZERS, ANTICONVULSANTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-05-13 | — | — | US | claimed |