Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367832 | 0.83 | CNR2 (0.43) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL10365911 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL10909585 | 0.73 | MEN1 (0.47) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL10365808 | 0.73 | MAPT (0.47) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL10909332 | 0.72 | MEN1 (0.46) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL10366286 | 0.72 | MEN1 (0.46) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL10367126 | 0.71 | MEN1 (0.44) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| Bromide SCHEMBL10366167 | 0.71 | MEN1 (0.44) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL10909576 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| Fumaric Acid SCHEMBL10366170 | 0.69 | GABRP (0.42) | ALDH1A1KMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167922-B1 | Pyrrolo [1,2-b] [1,2,5] triazepines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-03-28 | — | — | EP | disclosed |
| US-4588727-A | ANALGESICS, TRANQUILLIZERS, ANTICONVULSANTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0167922-A2 | Pyrrolo [1,2-b] [1,2,5] triazepines, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-01-15 | — | — | EP | disclosed |
| US-4517195-A | ANALGESICS, ANXIETY, ANTICONVULSANTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-05-14 | — | — | US | disclosed |