Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912088 | 0.98 | POLB (0.43) | POLBALDH1A1KMT2AKDM4EADORA2A | |
| SCHEMBL10911875 | 0.95 | L3MBTL1 (0.43) | POLBKMT2AADORA2AADORA1MAPT | |
| SCHEMBL10912048 | 0.89 | POLB (0.46) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10911744 | 0.87 | MAPT (0.53) | POLBKMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL10913826 | 0.87 | TERT (0.47) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10909758 | 0.86 | MAPT (0.44) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10911656 | 0.86 | POLB (0.45) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10913282 | 0.85 | MAPT (0.47) | POLBKMT2AKDM4EMAPTCHRNA7 | |
| SCHEMBL10914345 | 0.85 | POLB (0.44) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10911957 | 0.85 | POLB (0.42) | POLBALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |