SCHEMBL10909628

SCHEMBL10909628

CCNc1ccccc1-c1ccccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.52
KMT2A Q03164 3/20 0.50
MAPK1 P28482 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX12 P18054 1/20 0.49
GAA P10253 2/20 0.48
CLCN2 P51788 1/20 0.47
ALDH1A1 P00352 3/20 0.47
FABP3 P05413 1/20 0.47
FABP5 Q01469 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HTT P42858 1/20 0.46
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 1/20 0.46
AGTR1 P30556 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184136 0.85 ALDH1A1 (0.62) FABP4KMT2ASMN1; SMN2CYP3A4CYP2C9
SCHEMBL1168220 0.81 IDO1 (0.52) FABP4KMT2AMAPK1SMN1; SMN2MAPT
SCHEMBL10935587 0.81 FABP4 (0.61) FABP4KMT2ACLCN2ALDH1A1FABP3
SCHEMBL30491663 0.81 KDM4E (0.54) FABP4KMT2ASMN1; SMN2CYP3A4CYP2C9
SCHEMBL11674545 0.81 KDM4E (0.54) FABP4KMT2ASMN1; SMN2CYP3A4CYP2C9
SCHEMBL8267091 0.80 KMT2A (0.54) FABP4KMT2AMAPK1SMN1; SMN2CYP3A4
SCHEMBL17433851 0.79 FABP4 (0.56) FABP4KMT2AMAPK1SMN1; SMN2MAPT
SCHEMBL13073788 0.77 NPC1 (0.53) FABP4KMT2ASMN1; SMN2MAPTCYP3A4
SCHEMBL16181442 0.77 FABP4 (0.50) FABP4KMT2AMAPTCYP3A4CYP2C9
SCHEMBL10909632 0.77 FABP4 (0.64) FABP4KMT2AMAPK1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4624532-A IMPROVED COLOR FOR ELECTRO-OPTICAL DISPLAYS GENERAL ELECTRIC COMPANY (US) 1986-11-25 US disclosed
US-4356102-A Dichroic liquid crystal compositions containing anthraquinone-based dyes GENERAL ELECTRIC COMPANY (US) 1982-10-26 US disclosed