Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893103 | 0.78 | MTNR1A (0.69) | HTR1ACYP1A2NFKB1NPSR1BLM | |
| SCHEMBL11358975 | 0.78 | HTR2A (0.62) | HTR2ATRPM8MAPTHTR1AHTR1D | |
| SCHEMBL8202576 | 0.77 | HTR2A (0.61) | HTR2ATRPM8MAPTHTR1AHTR1D | |
| SCHEMBL14095640 | 0.77 | HTR2A (0.57) | HTR2ATRPM8MAPTHTR1AHTR1D | |
| SCHEMBL2540560 | 0.77 | CYP1A2 (0.63) | HTR2ATRPM8MAPTHTR1AHTR1D | |
| SCHEMBL7890134 | 0.76 | MTNR1A (0.64) | CYP1A2NFKB1NPSR1MEN1KMT2A | |
| SCHEMBL7850885 | 0.75 | HTR2A (0.63) | HTR2ATRPM8MAPTHTR1AHTR1D | |
| SCHEMBL9672887 | 0.74 | HTR2A (0.49) | HTR2AHTR2C | |
| SCHEMBL8711714 | 0.74 | MPO (0.51) | MAPTCYP1A2NFKB1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7683721 | 0.74 | NPSR1 (0.64) | HTR2ATRPM8MAPTHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614807-A | ANTIFERTILITY AGENTS | ELI LILLY AND COMPANY (US) | 1986-09-30 | — | — | US | disclosed |