Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | ESR1 | P03372 | 6/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HEXA | P06865 | 1/20 | 0.50 |
| ▸ | HEXB | P07686 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909819 | 0.89 | KDM4E (0.73) | KDM4EESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL10913053 | 0.88 | KDM4E (0.68) | KDM4EESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL10909659 | 0.86 | KDM4E (0.66) | KDM4EESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL9631706 | 0.85 | HDAC3 (0.59) | KDM4EESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL15056310 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL8619433 | 0.81 | KDM4E (0.53) | KDM4EESR1ESR2ALDH1A1MEN1 | |
| SCHEMBL3582064 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL17735857 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL10053599 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL5878681 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |