Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 2/20 | 0.60 |
| ▸ | HEXB | P07686 | 2/20 | 0.60 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991341 | 0.90 | ALDH1A1 (0.51) | HEXAHEXBANPEPDPP4KDM4E | |
| SCHEMBL31540930 | 0.85 | ANPEP (0.55) | HEXAHEXBANPEPDPP4KDM4E | |
| SCHEMBL14560522 | 0.82 | ANPEP (0.52) | ANPEPDPP4KDM4EMAPTMEN1 | |
| SCHEMBL3790518 | 0.82 | KMT2A (0.52) | ANPEPDPP4KDM4EMAPTMEN1 | |
| SCHEMBL4959465 | 0.81 | ANPEP (0.51) | ANPEPDPP4KDM4EMAPTMEN1 | |
| SCHEMBL12235610 | 0.81 | ANPEP (0.58) | ANPEPDPP4KDM4EMAPTMEN1 | |
| SCHEMBL10699832 | 0.80 | KMT2A (0.65) | ANPEPDPP4KDM4EMAPTMEN1 | |
| SCHEMBL14560523 | 0.80 | CDC25A (0.51) | ANPEPDPP4KDM4EMAPTMEN1 | |
| SCHEMBL15057224 | 0.79 | HEXA (0.69) | HEXAHEXBKDM4EMAPTMEN1 | |
| SCHEMBL29514557 | 0.79 | HEXA (0.69) | HEXAHEXBKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |