Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RGS12 | O14924 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HEXA | P06865 | 3/20 | 0.49 |
| ▸ | HEXB | P07686 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909813 | 0.90 | HEXA (0.60) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL14560522 | 0.86 | ANPEP (0.52) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL4959465 | 0.84 | ANPEP (0.51) | ALDH1A1KMT2AKDM4EMEN1PABPC1 | |
| SCHEMBL14560523 | 0.83 | CDC25A (0.51) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL10699832 | 0.83 | KMT2A (0.65) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL31540930 | 0.82 | ANPEP (0.55) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL526807 | 0.81 | KDM4E (0.68) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL29459619 | 0.81 | KDM4E (0.68) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL3790518 | 0.79 | KMT2A (0.52) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL10912457 | 0.79 | RAB9A (0.43) | ALDH1A1KMT2AMEN1PABPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121433-A | FOR DIAGNOSTIC, RESEARCH AND THERAPEUTIC USE; MIMIC OR MODULATE PROTEINS, ENZYMES, NUCLEIC ACIDS AND LIPIDS | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0746326-A4 | OLIGOMERIC COMPOUNDS HAVING NITROGEN-CONTAINING LINKAGES | ISIS PHARMACEUTICALS INC (US) | 2000-06-14 | — | — | EP | disclosed |
| EP-0746326-A1 | OLIGOMERIC COMPOUNDS HAVING NITROGEN-CONTAINING LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995018623-A1 | OLIGOMERIC COMPOUNDS HAVING NITROGEN-CONTAINING LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |