Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.54 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910956 | 1.00 | PLA2G4B (0.54) | PLA2G4BLPAR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10909228 | 0.90 | PLA2G4B (0.53) | PLA2G4BLPAR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10906893 | 0.90 | PLA2G4B (0.53) | PLA2G4BLPAR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL430650 | 0.82 | NR1H4 (0.50) | SMN1; SMN2TP53TSHR | |
| SCHEMBL10911020 | 0.79 | ALDH1A1 (0.50) | PLA2G4BNPC1RAB9AHTT | |
| SCHEMBL10911023 | 0.79 | ALDH1A1 (0.50) | PLA2G4BNPC1RAB9AHTT | |
| SCHEMBL10909118 | 0.79 | ALDH1A1 (0.50) | PLA2G4BNPC1RAB9AHTT | |
| SCHEMBL10909115 | 0.79 | ALDH1A1 (0.50) | PLA2G4BNPC1RAB9AHTT | |
| SCHEMBL7171686 | 0.79 | PLA2G4B (0.60) | PLA2G4BLPAR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20162273 | 0.79 | MEN1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496757-A | Ultraviolet-absorbing stabilizers substituted an aliphatic hydroxyl group | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | claimed |
| US-4618638-A | CAPABLE OF BINDING WITH ACRYLIC ENAMELS | CIBA-GEIGY CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| US-4544691-A | ACRYLIC AUTOMOBILE COATINGS; WEATHERPROOFING | CIBA-GEIGY CORPORATION (US) | 1985-10-01 | — | — | US | disclosed |
| US-4504419-A | Alpha-cyanocinnamate ultraviolet-absorbing stabilizers substituted by an aliphatic hydroxyl group | CIBA-GEIGY CORPORATION (US) | 1985-03-12 | — | — | US | disclosed |
| US-4496757-A | Ultraviolet-absorbing stabilizers substituted an aliphatic hydroxyl group | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| US-4496676-A | Ultraviolet-absorbing stabilizers substituted by an aliphatic hydroxyl group | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| US-4414393-A | BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |