SCHEMBL430650

SCHEMBL430650

CCCCOc1ccc(C=C(C(=O)OC)C(=O)OC)cc1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.50
ABCG2 Q9UNQ0 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
PDE4A P27815 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HIF1A Q16665 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
AHR P35869 1/20 0.48
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20162273 0.94 MEN1 (0.51) NR1H4ABCG2CYP1A2
SCHEMBL6380238 0.88 NR1H4 (0.47) NR1H4HDAC10HDAC6
SCHEMBL20162270 0.87 NR1H4 (0.56) NR1H4CYP1A2
SCHEMBL6484837 0.86 NR1H4 (0.46) NR1H4CYP1A2
SCHEMBL31483445 0.86 NR1H4 (0.56) NR1H4ABCG2KDM4ECYP1A2TP53
SCHEMBL11330304 0.86 NR1H4 (0.67) NR1H4ABCG2KDM4ECYP1A2SMN1; SMN2
SCHEMBL31483447 0.85 TLR4 (0.54) NR1H4TSHR
SCHEMBL12869940 0.85 NR1H4 (0.50) NR1H4CYP1A2
SCHEMBL19994224 0.84 TP53 (0.53) NR1H4ABCG2TP53TSHR
SCHEMBL141697 0.84 KDM4E (0.53) ABCG2KDM4ETP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617955-B2 Additive production process with a thermoplastic radically cross-linkable construction material STRATASYS, INC. (US) 2026-05-05 US disclosed
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes COVESTRO DEUTSCHLAND AG (DE) 2026-04-07 US disclosed
US-12447699-B2 Anisotropic composite materials based on polyisocyanates COVESTRO DEUTSCHLAND AG (DE) 2025-10-21 US disclosed
US-12331214-B2 Resistant 2K-PUR coatings COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2025-06-17 US disclosed
EP-3953407-B1 2-COMPONENT POLYURETHANE COATINGS WITH IMPROVED POT LIFE WITHOUT LOST WEATHERING STABILITY COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP disclosed
EP-3994192-B1 RESISTANT 2K-PUR COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP disclosed
CN-119841980-A Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2025-04-18 CN disclosed
CN-119841979-A Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2025-04-18 CN disclosed
EP-4058499-B1 POLYSILOXANE FUNCTIONALIZED POLYURETHANES FOR ENHANCING HYDROPHOBISATION OF SURFACES COVESTRO DEUTSCHLAND AG (DE) 2024-12-04 EP disclosed
EP-3554787-B1 METHOD FOR PRODUCING A 3D PRINTED FOAM-FILLED OBJECT STRATASYS INC (US) 2024-09-25 EP disclosed
EP-0021004-B1 SELFHARDENABLE MATERIAL FOR THE MANUFACTURE OF A WEATHER RESISTANT, NON YELLOWING ORTHOPEDIC BANDAGE BAYER AG (DE) 1982-08-04 EP disclosed
EP-0007502-B1 PROCESS FOR PREPARING FOAMED MOULDED MATERIALS BAYER AG (DE) 1981-12-30 EP disclosed
EP-0021004-A1 Selfhardenable material for the manufacture of a weather resistant, non yellowing orthopedic bandage BAYER AG (DE) 1981-01-07 EP disclosed
US-4189542-A Process for the production of foam moldings having an impervious outer skin using semi-prepolymer prepared from isocyanates such as isophorone diisocyanate BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
EP-0007502-A1 Process for preparing foamed moulded materials BAYER AG (DE) 1980-02-06 EP disclosed
EP-0001965-A1 Process for the preparation of foamed materials BAYER AG (DE) 1979-05-30 EP disclosed
US-4123418-A BIS-(U8I8I8L8L-PENTAMETHY TETRAMETHYL-4-PIPERIDYL)-SUBERATE CIBA-GEIGY CORPORATION (US) 1978-10-31 US disclosed
US-4110304-A STERICALLY HINDERED CYCLIC AMINE CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4061631-A STABILIZER CIBA-GEIGY CORPORATION (US) 1977-12-06 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617955-B2 Additive production process with a thermoplastic radically cross-linkable construction material UBE2G2, MTCL3, RAD51 NR1H4 4772/4885ABCG2 3837/4885KDM4E 1961/4885
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes TST, C9, ESD NR1H4 4624/4885ABCG2 4605/4885KDM4E 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.