SCHEMBL10910189

SCHEMBL10910189

CCCCCCCCCCCCCCCCCCN(c1nc(NCCCO)nc(N(CCCCCCCCCCCCCCCCCC)C2CC(C)(C)NC(C)(C)C2)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.38
SLC29A1 Q99808 3/20 0.34
DNM2 P50570 7/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9091672 0.96 SLC29A1 (0.35) KMT2ASLC29A1
SCHEMBL9861690 0.93 KMT2A (0.37) KMT2ASLC29A1
SCHEMBL13290125 0.93 DNM2 (0.34) KMT2ASLC29A1DNM2
SCHEMBL13415269 0.93 DNM2 (0.36) KMT2ASLC29A1DNM2
SCHEMBL3145900 0.93 DNM2 (0.36) KMT2ASLC29A1DNM2
SCHEMBL3131814 0.93 DNM2 (0.34) KMT2ASLC29A1DNM2
SCHEMBL11397203 0.92 KMT2A (0.41) KMT2ASLC29A1DNM2
SCHEMBL11401890 0.92 KMT2A (0.41) KMT2ASLC29A1DNM2
SCHEMBL11401394 0.92 KMT2A (0.41) KMT2ASLC29A1DNM2
SCHEMBL13415264 0.92 KMT2A (0.34) KMT2ASLC29A1DNM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0064752-B1 PHOSPHAZENES SUBSTITUTED BY PIPERIDYL GROUPS, PROCESS FOR PREPARING THEM, THEIR USE AS STABILIZERS AND POLYMER COMPOSITIONS STABILIZED BY THEM HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-08 EP disclosed
US-4476302-A PHOTOSTABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-09 US disclosed
US-4451400-A Phosphazenes useful as stabilizers in polymers HOECHST AKTIENGESELLSCHAFT (DE) 1984-05-29 US disclosed
EP-0064752-A2 Phosphazenes substituted by piperidyl groups, process for preparing them, their use as stabilizers and polymer compositions stabilized by them HOECHST AKTIENGESELLSCHAFT (DE) 1982-11-17 EP disclosed
EP-0061659-A1 Piperidine groups containing esters,methods for their preparation, their use as stabilising agents for polymers, and polymers containing these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-06 EP disclosed