SCHEMBL9861690

SCHEMBL9861690

CCCCN(c1nc(NCCCO)nc(NCCCO)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.37
SLC29A1 Q99808 3/20 0.35
KCNH3 Q9ULD8 1/20 0.32
GBA1 P04062 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9091672 0.98 SLC29A1 (0.35) KMT2ASLC29A1
SCHEMBL11101385 0.94 KMT2A (0.40) KMT2ASLC29A1GBA1
SCHEMBL10910189 0.93 KMT2A (0.38) KMT2ASLC29A1
SCHEMBL10813630 0.93 SLC29A1 (0.35) KMT2ASLC29A1
SCHEMBL9091458 0.92 SLC29A1 (0.39) KMT2ASLC29A1GBA1
SCHEMBL10816775 0.91 GBA1 (0.34) KMT2ASLC29A1KCNH3GBA1
SCHEMBL3136072 0.91 SLC29A1 (0.33) SLC29A1
SCHEMBL10167577 0.90 NPY1R (0.33) KMT2ASLC29A1
SCHEMBL9367814 0.90 DNM2 (0.34) KMT2AKCNH3
SCHEMBL11338890 0.89 SLC29A1 (0.33) KMT2ASLC29A1KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0176604-B1 HIGH-MOLECULAR PIPERIDINE GROUPS CONTAINED IN ESTERS, PROCESS FOR THEIR PREPARATION, THEIR USE AS STABILISERS FOR POLYMERS AND POLYMERS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-12 EP disclosed
EP-0176604-A2 High-molecular piperidine groups contained in esters, process for their preparation, their use as stabilisers for polymers and polymers containing them HOECHST AKTIENGESELLSCHAFT (DE) 1986-04-09 EP disclosed
US-4476302-A PHOTOSTABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-09 US disclosed
EP-0061659-A1 Piperidine groups containing esters,methods for their preparation, their use as stabilising agents for polymers, and polymers containing these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-06 EP disclosed