SCHEMBL109109

SCHEMBL109109

[c]1ccc2sc3ccccc3c2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.61
ALDH1A1 P00352 5/20 0.44
MAPT P10636 5/20 0.44
RAB9A P51151 3/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.38
MCL1 Q07820 1/20 0.36
IKBKB O14920 1/20 0.36
LIMK1 P53667 1/20 0.36
PNMT P11086 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
POLB P06746 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2393998 0.89 GPR3 (0.39) GPR3
SCHEMBL1965324 0.87 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL1334400 0.84 GPR3 (0.39) GPR3
SCHEMBL5168845 0.84 KDM4E (0.50) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL28138470 0.81 GPR3 (0.93) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL21295706 0.79 LIMK1 (0.40) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL28227583 0.78 GPR3 (0.88) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL28226769 0.78 GPR3 (0.88) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL14659543 0.78 GPR3 (1.00) GPR3ALDH1A1MAPTRAB9AHPGD
Dibenzothiophene SCHEMBL13294 0.78 GPR3 (1.00) GPR3ALDH1A1MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 754 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749631-B1 TRIARYLMETHANE COMPOUNDS MITSUBISHI GAS CHEMICAL CO (JP) 2024-03-06 EP claimed
WO-2024010050-A1 AMINE COMPOUND, AND ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTRONIC EQUIPMENT, AND ELECTRONIC ELEMENT CONTAINING SAME 保土谷化学工業株式会社 2024-01-11 WO claimed
US-20230391704-A1 TRIARYLMETHANE COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-07 US claimed
CN-116854599-A Tetraphenyl ethylene derivative and organic electroluminescent device comprising same 广东省大湾区华南理工大学聚集诱导发光高等研究院 2023-10-10 CN claimed
WO-2023074767-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 保土谷化学工業株式会社 2023-05-04 WO claimed
CN-108129431-B Fluorenonaphthofuran derivative and application thereof 北京鼎材科技有限公司 2023-04-07 CN claimed
CN-114497404-A Light emitting diode and amine compound used therefor 三星显示有限公司 2022-05-13 CN claimed
CN-112390811-B Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-03-04 CN claimed
CN-114057711-A Anthracene ketone spiro derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-02-18 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
US-5723072-A Photochromic heterocyclic fused indenonaphthopyrans PPG INDUSTRIES, INC. (US) 1998-03-03 US claimed
WO-1997048993-A1 NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS TRANSITIONS OPTICAL, INC. (US) 1997-12-24 WO claimed
US-5698141-A REVERSE CHARGE IN COLOR WHEN EXPOSURED TO ELECTROMAGNETIC RADIATION PPG INDUSTRIES, INC. (US) 1997-12-16 US claimed
US-5607926-A ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA MICROCIDE PHARMACEUTICALS, INC. (US) 1997-03-04 US claimed
EP-0754184-A1 CEPHALOSPORIN ANTIBIOTICS Microcide Pharmaceuticals, Inc. (US) 1997-01-22 EP claimed
EP-0530336-B1 CHIRAL PHOSPHINES HOFFMANN LA ROCHE (CH) 1996-03-06 EP claimed
WO-1996002517-A1 SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS DR. KARL THOMAE GMBH (DE) 1996-02-01 WO claimed
WO-1995026966-A1 CEPHALOSPORIN ANTIBIOTICS MICROCIDE PHARMACEUTICALS, INC. (US) 1995-10-12 WO claimed
US-5274125-A Chirale phosphines HOFFMANN-LA ROCHE INC. (US) 1993-12-28 US claimed
US-4973536-A LAMINATED STRUCTURE OF CHARGE GENERATING AND CHARGE TRANSPORTING LAYERS FUJI PHOTO FILM CO., LTD. (JP) 1990-11-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391704-A1 TRIARYLMETHANE COMPOUNDS CBR3, HAX1, HRH3 GPR3 236/4885ALDH1A1 2431/4885MAPT 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.