SCHEMBL10911366

SCHEMBL10911366

O=S(=O)(COc1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
HSD11B1 P28845 2/20 0.50
GAA P10253 1/20 0.49
AR P10275 1/20 0.48
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
PKM P14618 1/20 0.47
HTR1A P08908 1/20 0.44
HTR7 P34969 1/20 0.44
PSIP1 O75475 1/20 0.44
SCN4A P35499 2/20 0.44
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
DRD3 P35462 1/20 0.44
PGR P06401 2/20 0.43
PPARG P37231 2/20 0.43
PPARA Q07869 1/20 0.43
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4745383 0.93 AR (0.48) TDP1HSD11B1GAAARALDH1A1
SCHEMBL10914188 0.91 MEN1 (0.48) TDP1ARALDH1A1KMT2AMAPT
SCHEMBL6915896 0.87 PSIP1 (0.52) HSD11B1GAAALDH1A1PSIP1KMT2A
SCHEMBL10911432 0.83 MAPT (0.52) GAAALDH1A1SMN1; SMN2DRD2DRD4
SCHEMBL9030917 0.79 PSIP1 (0.44) HSD11B1ARALDH1A1PSIP1KMT2A
SCHEMBL10915082 0.78 HSD11B1 (0.54) HSD11B1ARALDH1A1PGRPPARG
SCHEMBL28496005 0.77 MAOB (0.58) HSD11B1GAAALDH1A1SMN1; SMN2KMT2A
SCHEMBL28675611 0.77 CA1 (0.48) TDP1ARALDH1A1KMT2AMEN1
SCHEMBL10914878 0.75 HTT (0.54) TDP1HSD11B1ARALDH1A1SMN1; SMN2
SCHEMBL10915304 0.74 MCL1 (0.50) TDP1GAAALDH1A1SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0119457-B1 AGENT FOR REGULATING THE GROWTH OF PLANTS BAYER AG (DE) 1986-12-30 EP disclosed
US-4588433-A SULFIDES, SULFOXIDES, SULFONES BAYER AKTIENGESELLSCHAFT (DE) 1986-05-13 US disclosed
EP-0119457-A1 Agent for regulating the growth of plants BAYER AG (DE) 1984-09-26 EP disclosed