Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700859 | 0.81 | DRD3 (0.61) | KDM4EHPGDHSD17B10ALDH1A1TDP1 | |
| SCHEMBL11713494 | 0.76 | DRD3 (0.65) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11716631 | 0.76 | KDM4E (0.56) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11713020 | 0.76 | KDM4E (0.66) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL10881020 | 0.74 | KDM4E (0.56) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL20241012 | 0.72 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11715065 | 0.71 | PIK3CG (0.48) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL9318828 | 0.70 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| Rosoxacin SCHEMBL135645 | 0.70 | CAPN1 (0.61) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 | |
| Rosoxacin SCHEMBL29361483 | 0.70 | CAPN1 (0.61) | KDM4EHPGDHSD17B10ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115049-B1 | 1-ETHYL-6,8-DIFLUORO-1,4-DIHYDRO-7-(1-IMIDAZOLYL)-4-OXOQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR PREPARING THE SAME AND ANTI-MICROBIAL COMPOSITIONS | KANEBO, LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |
| US-4530930-A | Antimicrobial 1-ethyl-6,8-difluoro-1,4-dihydro-7-(1-imidazolyl)-4-oxoquinoline-3-carboxylic acid derivatives | KANEBO, LTD. (JP) | 1985-07-23 | — | — | US | disclosed |
| EP-0115049-A1 | 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(1-imidazolyl)-4-oxoquinoline-3-carboxylic acid derivatives, process for preparing the same and anti-microbial compositions | KANEBO, LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |