Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Irloxacin SCHEMBL145215 | 0.85 | DRD3 (0.67) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| Irloxacin SCHEMBL9743701 | 0.84 | DRD3 (0.66) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| Irloxacin SCHEMBL9743690 | 0.84 | DRD3 (0.66) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26193950 | 0.82 | DRD3 (0.60) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10881020 | 0.81 | KDM4E (0.56) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9757197 | 0.81 | DRD3 (0.64) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10911972 | 0.81 | KDM4E (0.48) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL501895 | 0.80 | DRD3 (0.68) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10879645 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL11022977 | 0.78 | DRD3 (0.83) | DRD3KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098913-A | Bactericides for grampositive bacteria | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-03-24 | — | — | US | disclosed |