Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RPS6KA2 | Q15349 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL10912138 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| Dimethylamine SCHEMBL10911945 | 0.89 | KDM4E (0.53) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| Diethylamine SCHEMBL10910059 | 0.82 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL18391142 | 0.81 | KDM4E (0.82) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| Dimethylamine SCHEMBL10909606 | 0.80 | RPS6KA2 (0.51) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL22681989 | 0.79 | KDM4E (0.79) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL10911688 | 0.79 | KMT2A (0.61) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL22681991 | 0.79 | ALDH1A1 (0.69) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL26216143 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL10913041 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | claimed |