Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.56 |
| ▸ | CA1 | P00915 | 8/20 | 0.54 |
| ▸ | CA4 | P22748 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LIPC | P11150 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009374 | 0.75 | KDM4E (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10914045 | 0.72 | CA2 (0.56) | CA2CA1CA4CA12CA14 | |
| SCHEMBL564235 | 0.72 | CA2 (1.00) | CA2CA1CA4CA12CA14 | |
| SCHEMBL1845570 | 0.72 | FFAR1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10984165 | 0.72 | CA2 (0.59) | CA2CA1CA4CA12CA14 | |
| SCHEMBL7933436 | 0.72 | CA2 (0.82) | CA2CA1CA4CA12CA14 | |
| SCHEMBL30297744 | 0.71 | CA2 (1.00) | CA2CA1CA4CA12CA14 | |
| SCHEMBL81178 | 0.71 | CA2 (1.00) | CA2CA1CA4CA12CA14 | |
| SCHEMBL10913446 | 0.71 | CA2 (0.61) | CA2CA1CA4CA12CA14 | |
| SCHEMBL6978903 | 0.70 | CA2 (0.65) | CA2CA1CA4CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091367-B1 | BENZOTHIAZOLESULFONAMIDE DERIVATIVES FOR THE TOPICAL TREATMENT OF ELEVATED INTRAOCULAR PRESSURE | MERCK & CO. INC. (US) | 1986-06-18 | — | — | EP | claimed |