Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913089 | 1.00 | ALDH1A1 (0.34) | ALDH1A1TP53POLBCTDSP1TDP1 | |
| SCHEMBL11536395 | 0.71 | — | — | |
| SCHEMBL11536407 | 0.71 | — | — | |
| SCHEMBL8095277 | 0.65 | — | — | |
| SCHEMBL21983946 | 0.65 | — | — | |
| SCHEMBL18669476 | 0.65 | — | — | |
| SCHEMBL24220960 | 0.64 | SLC6A9 (0.40) | ALDH1A1TP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL13223389 | 0.64 | SLC6A9 (0.40) | ALDH1A1TP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3967181 | 0.64 | SLC6A9 (0.40) | ALDH1A1TP53CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL1133814 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040947-B1 | USE OF GUANIDINES FOR MANUFACTURING ANTIDIARRHOEAL MEDICAMENTS AND ANTIDIARRHOEAL COMPOSITIONS CONTAINING THESE GUANIDINES | JOHN WYETH & BROTHER LIMITED (GB) | 1986-12-03 | — | — | EP | disclosed |