Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441793 | 0.82 | SMN1; SMN2 (0.46) | CYP1A2CYP2A6MEN1KMT2AALDH1A1 | |
| SCHEMBL9441563 | 0.80 | ALDH1A1 (0.43) | ERN1ALDH1A1 | |
| SCHEMBL79252 | 0.79 | ERN1 (0.44) | ERN1CYP1A2CYP2A6MEN1KMT2A | |
| SCHEMBL1929437 | 0.79 | ERN1 (0.44) | ERN1CYP1A2CYP2A6MEN1KMT2A | |
| SCHEMBL3975312 | 0.79 | BRD9 (0.37) | ERN1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5171500 | 0.77 | PTGS2 (0.48) | ERN1 | |
| SCHEMBL10743288 | 0.77 | ALKBH3 (0.44) | ALDH1A1RAPGEF4 | |
| SCHEMBL29169368 | 0.77 | ERN1 (0.42) | ERN1CYP1A2CYP2A6MEN1KMT2A | |
| SCHEMBL11045347 | 0.77 | ERN1 (0.42) | ERN1CYP1A2CYP2A6MEN1KMT2A | |
| SCHEMBL28225789 | 0.77 | ERN1 (0.42) | ERN1CYP1A2CYP2A6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038061-B1 | SUBSTITUTED BIPHENYL-2-CARBOXALDEHYDES AND A PROCESS FOR PREPARING THEM | MERCK & CO. INC. (US) | 1985-01-23 | — | — | EP | claimed |
| US-4322563-A | Substituted biphenyl-2-carboxaldehydes | MERCK & CO., INC. (US) | 1982-03-30 | — | — | US | claimed |
| EP-0038061-A1 | Substituted biphenyl-2-carboxaldehydes and a process for preparing them | MERCK & CO. INC. (US) | 1981-10-21 | — | — | EP | claimed |
| US-4620025-A | NICKEL COMPLEX CATALYSTS | MERCK & CO., INC. (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0038061-B1 | SUBSTITUTED BIPHENYL-2-CARBOXALDEHYDES AND A PROCESS FOR PREPARING THEM | MERCK & CO. INC. (US) | 1985-01-23 | — | — | EP | disclosed |
| US-4322563-A | Substituted biphenyl-2-carboxaldehydes | MERCK & CO., INC. (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0038061-A1 | Substituted biphenyl-2-carboxaldehydes and a process for preparing them | MERCK & CO. INC. (US) | 1981-10-21 | — | — | EP | disclosed |