Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909622 | 0.92 | CA1 (0.55) | CA1CA2CA9CA4CA12 | |
| SCHEMBL10912078 | 0.85 | CA1 (0.44) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11314968 | 0.84 | CA1 (0.63) | CA1CA2CA9CA4CA12 | |
| SCHEMBL28473866 | 0.84 | CA1 (0.55) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11307275 | 0.83 | POLB (0.64) | CA1CA2CA9CA4CA12 | |
| SCHEMBL3774059 | 0.82 | ALDH1A1 (0.52) | TDP1ALDH1A1L3MBTL1LMNAAGTR1 | |
| SCHEMBL8091427 | 0.82 | CA1 (0.60) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11306933 | 0.82 | CA1 (0.60) | CA1CA2CA9CA4CA12 | |
| SCHEMBL8090181 | 0.80 | CA1 (0.58) | CA1CA2CA9CA4CA12 | |
| SCHEMBL6961551 | 0.79 | CA1 (0.59) | CA1CA2CA9CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |