Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912457 | 0.92 | RAB9A (0.43) | CA1CA2CA9CA4RAB9A | |
| SCHEMBL10913396 | 0.85 | CA1 (0.57) | CA1CA2CA9CA4RAB9A | |
| SCHEMBL3774059 | 0.84 | ALDH1A1 (0.52) | RAB9ANPC1KMT2AALDH1A1LMNA | |
| SCHEMBL10913894 | 0.80 | AHR (0.47) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL10909793 | 0.79 | KMT2A (0.42) | RAB9ANPC1ATMMEN1KMT2A | |
| Dimethylamine SCHEMBL10914075 | 0.78 | RAB9A (0.43) | RAB9ANPC1ATMMEN1KMT2A | |
| SCHEMBL10909622 | 0.77 | CA1 (0.55) | CA1CA2CA9CA4ATM | |
| SCHEMBL10909813 | 0.77 | HEXA (0.60) | RAB9ANPC1ATMANPEPDPP4 | |
| SCHEMBL10914068 | 0.77 | PABPC1 (0.45) | RAB9ANPC1ATMMEN1KMT2A | |
| Dimethylamine SCHEMBL10912082 | 0.77 | RAB9A (0.45) | RAB9ANPC1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |