Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563104 | 0.87 | PDE4D (0.46) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL10377541 | 0.83 | NPC1 (0.50) | ALDH1A1PKMMEN1KMT2APOLB | |
| SCHEMBL10377358 | 0.83 | NPC1 (0.50) | ALDH1A1PKMMEN1KMT2APOLB | |
| SCHEMBL10915430 | 0.81 | ALDH1A1 (0.46) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL6960006 | 0.80 | ALDH1A1 (0.54) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL6960011 | 0.80 | ALDH1A1 (0.54) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL10375543 | 0.80 | NPC1 (0.52) | ALDH1A1PKMMAPTPDE4DPDE4B | |
| SCHEMBL10375282 | 0.80 | ALDH1A1 (0.55) | ALDH1A1PKMMEN1KMT2APOLB | |
| SCHEMBL10724090 | 0.79 | MAPT (0.49) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL10377412 | 0.79 | ALDH1A1 (0.46) | ALDH1A1PKMMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204317-A2 | 2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters | E.R. Squibb & Sons, Inc. (US) | 1986-12-10 | — | — | EP | disclosed |