Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.77 |
| ▸ | PPARG | P37231 | 7/20 | 0.77 |
| ▸ | PPARD | Q03181 | 7/20 | 0.77 |
| ▸ | PPARA | Q07869 | 7/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TLR2 | O60603 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL17101371 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Tetrabuthylammonium SCHEMBL8778048 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Tetrabuthylammonium SCHEMBL1716194 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Tetrabuthylammonium SCHEMBL2230012 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Tetrabuthylammonium SCHEMBL3748554 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Tetrabuthylammonium SCHEMBL28280586 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Tetrabuthylammonium SCHEMBL2230705 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL5152853 | 1.00 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5535683 | 0.98 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5533401 | 0.98 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863816-B | Preparation method and application of hydrophilic quaternary ammonium type biocompatible ionic liquid | 浙江大学 | 2021-05-18 | — | — | CN | disclosed |
| CN-107810204-B | Composition for immediate termination of free radical polymerization | 巴斯夫欧洲公司 | 2020-04-14 | — | — | CN | disclosed |
| US-10221255-B2 | Composition for the immediate stopping of a free-radical polymerization | BASF SE (DE) | 2019-03-05 | — | — | US | disclosed |
| EP-2426558-B1 | Silicon-containing film-forming composition, silicon-containing film-formed substrate, and patterning process | SHINETSU CHEMICAL CO (JP) | 2018-10-24 | — | — | EP | disclosed |
| EP-2744335-B1 | COMPOSITION COMPRISING ACTIVE INGREDIENT, OIL AND IONIC LIQUID | BASF SE (DE) | 2018-10-10 | — | — | EP | disclosed |
| US-20180171035-A1 | COMPOSITION FOR THE IMMEDIATE STOPPING OF A FREE-RADICAL POLYMERIZATION | BASF SE (DE) | 2018-06-21 | — | — | US | disclosed |
| US-9949475-B2 | Composition comprising active ingredient, oil and ionic liquid | BASF SE (DE) | 2018-04-24 | — | — | US | disclosed |
| CN-107810204-A | For terminating the composition of radical polymerization immediately | 巴斯夫欧洲公司 | 2018-03-16 | — | — | CN | disclosed |
| EP-2500775-B1 | PATTERNING PROCESS AND COMPOSITION FOR FORMING SILICON-CONTAINING FILM USABLE THEREFOR | SHINETSU CHEMICAL CO (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-8951711-B2 | Patterning process and composition for forming silicon-containing film usable therefor | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-02-10 | — | — | US | disclosed |
| US-20030204025-A1 | Blending hexamethylene diamine curative agent with an ethylene/alkyl acrylate copolymer containing a monoalkyl ester of a 1,4-butene-dioic acid cure-site termonomer, heating, pressurization to crosslink, heating | DUPONT POLYMERS, INC. | 2003-10-30 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0769517-B1 | SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT | DAIKIN IND LTD (JP) | 2002-09-18 | — | — | EP | disclosed |
| JP-2000336337-A | NEW FOAMING AGENT | OTSUKA CHEM CO LTD | 2000-12-05 | — | — | JP | disclosed |
| CN-1231669-A | Phase transfer catalysts for the synthesis of polyol fatty acid polyesters | PROCTER & GAMBLE (US) | 1999-10-13 | — | — | CN | disclosed |
| US-5684065-A | LASER BEAM | DAIKIN INDUSTRIES, LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0769517-A1 | SURFACE-MODIFIED FLUORORESIN MOLDED PRODUCT | DAIKIN INDUSTRIES, LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-5066743-A | Bonding nonpolar surfaces such as polyethylene and polypropylene | LOCTITE CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| US-4979993-A | Trialkylammonium alkyl carboxylate primer for cyanoacrylate bonding of polymeric substrates | LOCTITE CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| CN-1032444-A | Make polyacrylate polymers sulfurized vulcanization process without issue | GOODRICH CO B F (US) | 1989-04-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221255-B2 | Composition for the immediate stopping of a free-radical polymerization | FASTKD5, TYK2, FASTKD1 | GPR84 4770/4885PPARG 2428/4885PPARD 2176/4885 |
| US-20180171035-A1 | COMPOSITION FOR THE IMMEDIATE STOPPING OF A FREE-RADICAL POLYMERIZATION | FASTKD5, TYK2, FASTKD1 | GPR84 4770/4885PPARG 2428/4885PPARD 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.