⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27545450 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL17363299 | 0.97 | — | — | |
| Pyrrolidine SCHEMBL15346082 | 0.85 | ALDH1A1 (0.35) | — | |
| Thiophene SCHEMBL28206024 | 0.83 | PARP1 (0.32) | — | |
| Piperidine SCHEMBL15346185 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL17912372 | 0.80 | — | — | |
| SCHEMBL2590838 | 0.73 | — | — | |
| SCHEMBL280044 | 0.71 | — | — | |
| SCHEMBL4973414 | 0.66 | — | — | |
| SCHEMBL6053208 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2949 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791497-A | Valerolactone natural product molecule parthenolide/dehydrocostus lactone spliced pyrrolinone spiro-oxindole, and preparation method and application thereof | 咸阳师范学院 | 2024-10-18 | — | — | CN | claimed |
| CN-118638127-A | Double spiro [ pyrrolinone-oxindole-hexahydroshanone ] spliced compound and preparation method and application thereof | 咸阳师范学院 | 2024-09-13 | — | — | CN | claimed |
| CN-118453568-A | Application of organic compound in preparation of antibacterial and antitumor compound | 中国科学技术大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118360010-A | Self-sealing rubber composition for tire, self-sealing rubber and preparation method of self-sealing rubber | 大冢材料科技（上海）有限公司 | 2024-07-19 | — | — | CN | claimed |
| WO-2024074436-A1 | LACTATE ENHANCING COMPOUNDS AND USES THEREOF | GLIAPHARM SA (CH) | 2024-04-11 | — | — | WO | claimed |
| CN-115850277-B | Peganum harmala skeleton spliced multi-spiro pyrrolinones derivative and preparation method and application thereof | 贵州大学 | 2024-03-08 | — | — | CN | claimed |
| CN-112592306-B | Pyrrolinones and synthesis method thereof | 百顺药业有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-114805168-B | Pyrrolinones and synthesis method thereof | 百顺药业有限公司 | 2024-01-09 | — | — | CN | claimed |
| EP-4269387-A1 | PYRROLINONE COMPOUND AND SYNTHESIS METHOD THEREFOR | Poseidon Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | claimed |
| US-20230321131-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT AND PREVENTION OF AN ANTINEOPLASTIC-INDUCED TOXICITY | NUVAMID SA (CH) | 2023-10-12 | — | — | US | claimed |
| CN-1055240-A | A kind of manufacture method of available chlorine indicator paper | XI AN CENTRAL EPIDEMIC PREVENT (CN) | 1991-10-09 | — | — | CN | claimed |
| EP-0397474-A2 | Photosensitive composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1990-11-14 | — | — | EP | claimed |
| EP-0184981-B1 | PYRROLINONES AND THEIR INTERMEDIATE PRODUCTS | CIBA-GEIGY AG (CH) | 1989-08-23 | — | — | EP | claimed |
| US-4812445-A | Starch based encapsulation process | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-03-14 | — | — | US | claimed |
| EP-0281692-A1 | Additive for lubricants and hydrocarbon fuels comprising reaction products of olefins, sulfur, hydrogen sulfide and nitrogen containing polymeric compounds | MOBIL OIL CORPORATION (US) | 1988-09-14 | — | — | EP | claimed |
| US-4755397-A | Slurrying starch and material in saturated aqueous salt solution, dispersing by injecting steam, reducing pressure, recovering precipitated encapsulated material | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-07-05 | — | — | US | claimed |
| US-4749795-A | Phenyl substituted pyrrolinones | CIBA-GEIGY CORPORATION (US) | 1988-06-07 | — | — | US | claimed |
| US-4737442-A | INCLUDING A SENSITIZER AND A BLOCKED DEVELOPMENT RESTRAINER; FREE OF BLACK SPOTS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-12 | — | — | US | claimed |
| US-4661274-A | Additive for lubricants and hydrocarbon fuels comprising reaction products of olefins, sulfur, hydrogen sulfide and nitrogen containing polymeric compounds | MOBIL OIL CORPORATION (US) | 1987-04-28 | — | — | US | claimed |
| EP-0005143-B1 | 1-BENZOYL-2-PYRROLIDINONE DERIVATIVE, PROCESSES FOR ITS PREPARATION AND MEDICAMENTS CONTAINING IT | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-07-14 | — | — | EP | claimed |