⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915 | 0.73 | — | — | |
| SCHEMBL4113248 | 0.73 | — | — | |
| Hydrogen Sulfide SCHEMBL27545450 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL17363299 | 0.71 | — | — | |
| SCHEMBL6223914 | 0.67 | — | — | |
| Pyrrolidine SCHEMBL15346082 | 0.62 | ALDH1A1 (0.35) | — | |
| SCHEMBL17912372 | 0.61 | — | — | |
| Piperidine SCHEMBL15346185 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL9525717 | 0.59 | — | — | |
| SCHEMBL723377 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566864-A2 | PYRIDAZINONES AS GPR119 AGONISTS | Boehringer Ingelheim International GmbH (DE) | 2013-03-13 | — | — | EP | claimed |
| WO-2011138427-A2 | PYRIDAZINONES AS GPR119 AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-10 | — | — | WO | claimed |
| CN-1071090-C | composition with synergistic fungicidal action | ROHM & HAAS (US) | 2001-09-19 | — | — | CN | claimed |
| CN-1189293-A | Pyridazinones as marine antifouling agents | ROHM & HAAS (US) | 1998-08-05 | — | — | CN | claimed |
| CN-1038249-C | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM & HAAS (US) | 1998-05-06 | — | — | CN | claimed |
| CN-1146282-A | Composition with synergistic mycotoxicity effect | ROHM & HAAS (US) | 1997-04-02 | — | — | CN | claimed |
| CN-1069729-A | Dihydropyridazinone, pyridazinone and related compound thereof as sterilant | ROHM & HAAS (US) | 1993-03-10 | — | — | CN | claimed |
| EP-0515257-A1 | 1-phenyl-1,4-dihydro-3-hydroxy-4-oxo-pyridazine derivatives, their preparation and their therapeutic use | PIERRE FABRE MEDICAMENT (FR) | 1992-11-25 | — | — | EP | claimed |
| EP-0175363-B1 | 4,5-DIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1990-01-17 | — | — | EP | claimed |
| CN-117460723-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115003296-A | Compounds and methods for treating cystic fibrosis | 弗拉特利发现实验室有限责任公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-113646050-A | Thieno [3,2-B ] pyrrolo [3,2-D ] pyridazinone derivatives and their use as PKM2 derivatives for the treatment of cancer, obesity and diabetes related disorders | 安吉奥斯医药品有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-103690542-B | Poly-(ADP-ribose) AG14361 | ABBVIE INC. (US) | 2015-11-18 | — | — | CN | disclosed |
| CN-103690542-A | Inhibitors of poly(ADP-ribose)polymerase | ABBVIE INC | 2014-04-02 | — | — | CN | disclosed |
| CN-1071090-C | composition with synergistic fungicidal action | ROHM & HAAS (US) | 2001-09-19 | — | — | CN | disclosed |
| CN-1038249-C | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM & HAAS (US) | 1998-05-06 | — | — | CN | disclosed |
| CN-1146282-A | Composition with synergistic mycotoxicity effect | ROHM & HAAS (US) | 1997-04-02 | — | — | CN | disclosed |
| CN-1143637-A | Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides | ROHM & HAAS (US) | 1997-02-26 | — | — | CN | disclosed |
| CN-1069729-A | Dihydropyridazinone, pyridazinone and related compound thereof as sterilant | ROHM & HAAS (US) | 1993-03-10 | — | — | CN | disclosed |
| EP-0515257-A1 | 1-phenyl-1,4-dihydro-3-hydroxy-4-oxo-pyridazine derivatives, their preparation and their therapeutic use | PIERRE FABRE MEDICAMENT (FR) | 1992-11-25 | — | — | EP | disclosed |