Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304752 | 0.91 | GAA (0.44) | TSHRGAALMNAL3MBTL1TDP1 | |
| SCHEMBL11404881 | 0.89 | MAPT (0.50) | LMNAL3MBTL1KMT2AMEN1HPGD | |
| SCHEMBL10877255 | 0.89 | TSHR (0.42) | TSHRGAALMNATDP1KMT2A | |
| SCHEMBL10839775 | 0.88 | GAA (0.43) | TSHRGAAL3MBTL1TDP1KMT2A | |
| SCHEMBL10916449 | 0.87 | L3MBTL1 (0.43) | TSHRGAALMNAL3MBTL1TDP1 | |
| SCHEMBL8508876 | 0.87 | MAPT (0.53) | TSHRGAALMNAL3MBTL1TDP1 | |
| SCHEMBL10838863 | 0.86 | CYP1A2 (0.43) | GAALMNATDP1HPGDSMN1; SMN2 | |
| SCHEMBL10953475 | 0.86 | MAPT (0.39) | TSHRGAALMNAL3MBTL1TDP1 | |
| SCHEMBL9587752 | 0.85 | MAPT (0.45) | LMNAL3MBTL1KMT2AMEN1HPGD | |
| Hydrochloric Acid SCHEMBL10947196 | 0.85 | CYP1A2 (0.43) | GAALMNATDP1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029319-B1 | QUINOLINYLOXY(AMINO)PHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR SYNTHESIS, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1986-01-15 | — | — | EP | disclosed |
| US-4444584-A | Ethyl 2[4-(7-chloroquinolin-3-yloxy)phenoxy]propionate, the N-oxide, and herbicidal compositions and methods employing them | ICI AUSTRALIA LIMITED (AU) | 1984-04-24 | — | — | US | disclosed |
| EP-0029319-A2 | Quinolinyloxy(amino)phenoxyalkane carboxylic acid derivatives, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-05-27 | — | — | EP | disclosed |