Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984246 | 0.87 | ALDH1A1 (0.53) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11015791 | 0.87 | ALDH1A1 (0.48) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10915307 | 0.86 | TSHR (0.46) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11304752 | 0.84 | GAA (0.44) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL11404881 | 0.83 | MAPT (0.50) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10838863 | 0.81 | CYP1A2 (0.43) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8677802 | 0.81 | MAPT (0.48) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL10947196 | 0.80 | CYP1A2 (0.43) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9587752 | 0.80 | MAPT (0.45) | MAPTLMNASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10839077 | 0.79 | MAPT (0.42) | MAPTLMNASMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052798-B1 | OXIME ESTERS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND COMPOSITIONS CONTAINING THESE ESTERS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-05-08 | — | — | EP | claimed |
| US-4435207-A | Quinyloxy-phenyloxy-oxime ester compounds having herbicidal activity | HOFFMANN-LA ROCHE INC. (US) | 1984-03-06 | — | — | US | claimed |
| US-4545807-A | Oxime ester herbicides | HOFFMANN-LA ROCHE INC. (US) | 1985-10-08 | — | — | US | disclosed |
| US-4435207-A | Quinyloxy-phenyloxy-oxime ester compounds having herbicidal activity | HOFFMANN-LA ROCHE INC. (US) | 1984-03-06 | — | — | US | disclosed |