Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453941 | 0.79 | MEN1 (0.77) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30557461 | 0.79 | MEN1 (0.77) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4005968 | 0.79 | HPGD (0.66) | CYP1A2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30254346 | 0.79 | HPGD (0.66) | CYP1A2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL862993 | 0.77 | CYP1A2 (0.75) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2865596 | 0.77 | CYP1A2 (0.69) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28879952 | 0.77 | ALDH1A1 (0.56) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1886408 | 0.76 | CYP1A2 (1.00) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25202109 | 0.74 | CYP1A2 (0.65) | CYP1A2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11674611 | 0.74 | KMT2A (0.75) | CYP1A2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0064878-A1 | Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |